Discovery of Pyridinone Derivatives as Potent, Selective, and Orally Bioavailable Adenosine A2A Receptor Antagonists for Cancer Immunotherapy

Autor: Chenyu Zhu, Shuyin Ze, Ronghui Zhou, Xinyu Yang, Haojie Wang, Xiaolei Chai, Meimiao Fang, Mingyao Liu, Yonghui Wang, Weiqiang Lu, Qiong Xie
Rok vydání: 2023
Předmět:
Zdroj: Journal of Medicinal Chemistry. 66:4734-4754
ISSN: 1520-4804
0022-2623
DOI: 10.1021/acs.jmedchem.2c01860
Databáze: OpenAIRE