Aging Effect on Lamina Cribrosa Depth in Ocular Hypertension and Glaucoma

Autor: Claude F. Burgoyne, Ruojin Ren, Hongli Yang, Christy Hardin, Stuart K. Gardiner, Shaban Demirel
Rok vydání: 2019
Předmět:
Zdroj: Intraocular and Intracranial Pressure Gradient in Glaucoma ISBN: 9789811321368
DOI: 10.1007/978-981-13-2137-5_29
Popis: In clinic, “deep” vs. “shallow” cupping is well established in human glaucoma. Our central hypothesis is that the “shallow” or senile sclerotic cupping of aged eyes is a manifestation of their stiffer connective tissues. We predicted that there are age-related differences in structure/function relationships. The relationship between the magnitude of laminar deformation and visual field loss will be different in young (“compliant”) eyes compared to old (“stiff”) eyes.
Databáze: OpenAIRE