Radioimmunoguided surgery (RIGS), PET/CT image-guided surgery, and fluorescence image-guided surgery: Past, present, and future

Autor: Mark Bloomston, Edward W. Martin, Mark Arnold, Osama Al-Saif, George H. Hinkle, Duxin Sun, Stephen P. Povoski, Nathan Hall
Rok vydání: 2007
Předmět:
Zdroj: Journal of Surgical Oncology. 96:297-308
ISSN: 0022-4790
Popis: 125I-labeled anti-TAG-72 antibodies were applied in radioimmunoguided surgery (RIGS) to remove gross and occult tumors. It is challenging to handle 125I-labeled materials. PET/CT image-guided surgery utilizes 18FDG to monitor the biochemical activity of the tumor and to integrate pre- and postoperative imaging for complete tumor removal. PET/CT image-guided surgery only detects later stage disease. Fluorescence image-guided surgery using anti-TAG-72 antibodies may provide opportunities for intraoperative cancer detection of both gross and occult tumors. J. Surg. Oncol. 2007;96:297–308. © 2007 Wiley-Liss, Inc.
Databáze: OpenAIRE