Morphological and Immunohistochemical Features of the Heart under the Effect of Hydrogen Sulfide Balneotherapy
| Autor: | N. I. Gulyaeva, G. G. Freind, E. V. Vladimirskii, V. E. Vladimirskii |
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| Rok vydání: | 2021 |
| Předmět: |
0301 basic medicine
Balneotherapy Chemistry medicine.medical_treatment Hydrogen sulfide Mesenchymal stem cell H&E stain CD34 General Medicine Endoglin Molecular biology General Biochemistry Genetics and Molecular Biology 03 medical and health sciences chemistry.chemical_compound 030104 developmental biology 0302 clinical medicine medicine Immunohistochemistry CD90 030217 neurology & neurosurgery |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 171:270-275 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/s10517-021-05210-7 |
| Popis: | The effects of hydrogen sulfide baths and sulfide-silt mud applications on the abdominal wall were studied in outbred white rats. Heart preparations stained with hematoxylin and eosin were analyzed and the mean numbers of cells expressing Ki-67, Nkx-2.5, and mesenchymal stem cell markers were determined. Hydrogen sulfide balneotherapy promoted the development of blood capillaries in rat hearts and an increased the expression of CD34. A decrease in the regenerative potential of the myocardium was found due to a decrease in the content of proliferating cells and cells expressing CD73, CD90, and CD105, and also due to the absence of cells stained for cardiomyogenic differentiation marker Nkx-2.5. |
| Databáze: | OpenAIRE |
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