Phase 2 trial of pembrolizumab (PEM) plus granulocyte macrophage colony stimulating factor (GM-CSF) in advanced biliary cancers (ABC): Clinical outcomes and biomarker analyses

Autor:	Jimmy Hwang, Spencer C. Behr, Zoe Quandt, Emily Mitchell, Katherine Van Loon, Zoe Ngo, Robin Kate Kelley, Sarah E. Umetsu, Chloe E. Atreya, Bridget P. Keenan, Andrew H. Ko, Thomas Weber, Alan P. Venook, Pelin Cinar, Chienying Liu, Lawrence Fong, John D. Gordan
Rok vydání:	2018
Předmět:	0301 basic medicine Cancer Research Myeloid business.industry medicine.medical_treatment Pembrolizumab Biliary cancer Immune checkpoint 03 medical and health sciences 030104 developmental biology 0302 clinical medicine medicine.anatomical_structure Granulocyte macrophage colony-stimulating factor Cytokine Oncology 030220 oncology & carcinogenesis medicine Cancer research Overall survival Biomarker (medicine) business medicine.drug
Zdroj:	Journal of Clinical Oncology. 36:4087-4087
ISSN:	1527-7755 0732-183X
Popis:	4087Background: The efficacy of immune checkpoint inhibition (CPI) has not been established in ABC. The combination of CPI plus the myeloid cytokine GM-CSF was safe with prolonged overall survival ...
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::277ed036e579fa115f0bd69452fc1119 https://doi.org/10.1200/jco.2018.36.15_suppl.4087 Zobrazit plný text záznamu