Non-valvular Infective Endocarditis Caused by Sarocladium kiliense in an Immunocompromised Patient with Aplastic Anemia

Autor:	Yasushi Kubota, Jun Ando, Somay Yamagata Murayama, Tadashi Mori, Shinya Kimura, Michiaki Akashi, Yutaro Mine, Hiroaki Kitamura, Rika Tomimasu, Masaharu Miyahara
Rok vydání:	2022
Předmět:	business.industry Immunocompromised patient General Medicine medicine.disease law.invention Microbiology Causative organism law Infective endocarditis Internal Medicine medicine Endocarditis Sarocladium kiliense Aplastic anemia business Polymerase chain reaction Fungal hyphae
Zdroj:	Internal Medicine. 61:1279-1283
ISSN:	1349-7235 0918-2918
DOI:	10.2169/internalmedicine.7536-21
Popis:	Sarocladium kiliense is ubiquitous in the human environment and is an emerging opportunistic pathogen, especially among immunocompromised hosts. A 77-year-old man diagnosed with aplastic anemia suffered from non-valvular endocarditis. After he passed away, fungal hyphae were observed in several lesions on a postmortem examination. Polymerase chain reaction (PCR) and a DNA sequence analysis revealed S. kiliense as the causative organism. This is the first case report of non-valvular fungal endocarditis caused by S. kiliense identified by PCR and a DNA sequence analysis in an immunocompromised patient. Although rare, invasive fungal infection caused by S. kiliense should be considered in immunocompromised hosts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::27728db86af3c0ea7780ed8bda8bb94b https://doi.org/10.2169/internalmedicine.7536-21 Zobrazit plný text záznamu