Serum Antioxidant Enzymes, Haematological Values and Uric Acid Concentrations in Prostatic Disease Patients: An Investigative Study

Autor: Nwaogazi N. Edith, Agbugba N. Agnes, Achi K. Ngozi, Ohaeri O. Christopher, R. I. Uroko, Ijioma N. Solomon
Rok vydání: 2021
Předmět:
Zdroj: International Blood Research & Reviews. :31-38
ISSN: 2321-7219
Popis: Aim: In this study, the haematology, serum antioxidant enzymes, and uric acid concentrations in prostatic disease patients attending the Nephrology Department of Abia State University Teaching Hospital, Aba were evaluated. Methodology: A total of one hundred and ten (110) adult males (aged 40-80 years) comprising of sixty (60) prostatic disease patients and 50 normal subjects were recruited. The prostatic disease patients comprised of 30 prostatitis, 20 Benign Prostatic Hyperplasia (BPH), and 10 prostate cancer patients. Haematological parameters, antioxidant enzyme levels, and uric acid concentration were determined on blood samples collected from the subjects between January 2017 and December 2019. Results: Results obtained following analysis indicated a significant fall in red blood cell count, haematocrit levels and haemoglobin concentrations in all the prostatic disease patients when compared with control subjects (p0.05). Leukocyte and lymphocyte counts in the patients also did not significantly differ from those of the control subjects (p>0.05) but platelets counts were significantly lower (p
Databáze: OpenAIRE