Yellow fever in Central Uganda, 1964 Part III. Virus isolation from man and laboratory studies

Autor: D. I. H. Simpson, M. C. Williams, J. P. Woodall
Rok vydání: 1965
Předmět:
Zdroj: Transactions of the Royal Society of Tropical Medicine and Hygiene. 59:444-448
ISSN: 0035-9203
DOI: 10.1016/0035-9203(65)90064-7
Popis: Yellow fever virus was isolated and re-isolated in mice from the serum and cerebral fluid of a patient who died in central Uganda in May 1964. Provisional identification was made within 48 hours of the first mice sickening, by the use of the haemagglutination-inhibition test. This was confirmed by a later reciprocal cross-neutralization test with the French neurotropic strain of yellow fever virus, and by the typical histological appearances of the liver of a rhesus monkey, destroyed when febrile after inoculation with infected mouse brains.
Databáze: OpenAIRE