Acrylamide-induced carcinogenicity in mouse lung involves mutagenicity:cIIgene mutations in the lung of big blue mice exposed to acrylamide and glycidamide for up to 4 weeks

Autor:	Mugimane G. Manjanatha, Sharon D. Shelton, Daniel R. Doerge, Li-Wu Guo
Rok vydání:	2015
Předmět:	Genetics Lung Epidemiology Chemistry Health Toxicology and Mutagenesis Metabolite Gene mutation Molecular biology In vitro chemistry.chemical_compound medicine.anatomical_structure Glycidamide Acrylamide medicine Mouse Lung Genetics (clinical) Carcinogen
Zdroj:	Environmental and Molecular Mutagenesis. 56:446-456
ISSN:	0893-6692
DOI:	10.1002/em.21939
Popis:	Potential health risks for humans from exposure to acrylamide (AA) and its epoxide metabolite glycidamide (GA) have garnered much attention lately because substantial amounts of AA are present in a variety of fried and baked starchy foods. AA is tumorigenic in rodents, and a large number of in vitro
Databáze:	OpenAIRE
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