Chemical modification of human IgG as a method of demonstrating differences between properties of antibodies and natural antiglobulins (homoreactants)

Autor:	Bartova Lm, A. Ya. Kul'berg, E. V. Fishevskaya
Rok vydání:	1979
Předmět:	biology Chemical modification General Medicine Molecular biology General Biochemistry Genetics and Molecular Biology Microbiology chemistry.chemical_compound chemistry Reagent biology.protein Sodium thiocyanate Antibody Antitoxin Incubation Sodium Deoxycholate
Zdroj:	Bulletin of Experimental Biology and Medicine. 88:1327-1330
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf00835587
Popis:	Naturally arising antiglobulin factors, or homoreactants (HR) contained in preparations of human IgG are inactivated by incubation in a solution of sodium thiocyanate (3–5 M) and sodium deoxycholate (0.005 M). Staphylococcal antitoxin contained in the same human IgG preparations is resistant to the action of these reagents. The results point to differences in the structure of HR and antibodies.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::272593d458fccd66a22d565061a3d3f4 https://doi.org/10.1007/bf00835587 Zobrazit plný text záznamu Full text from SpringerLink