Super-early images of brain perfusion SPECT using 123I-IMP for the assessment of hyperperfusion in stroke patients

Autor: Yutaka Abe, Yusuke Inoue, Toshimasa Hara, Keita Takahashi, Hiroki Miyatake, Tomomi Ikari
Rok vydání: 2018
Předmět:
Zdroj: Annals of Nuclear Medicine. 32:695-701
ISSN: 1864-6433
0914-7187
DOI: 10.1007/s12149-018-1293-5
Popis: With the advancement of reperfusion therapy in stroke patients, assessment of perfusion status after therapy is gaining importance. Hyperperfusion tends to be underestimated by the conventional early imaging of 123I-IMP brain perfusion SPECT. We evaluated the utility of super-early imaging as an adjunct to early imaging for the assessment of postischemic hyperperfusion in stroke patients. Sixty-seven patients who underwent 123I-IMP brain perfusion SPECT within 14 days after the onset of cerebral infarction were retrospectively analyzed. Super-early (4–10 min) and early (15–45 min) images were acquired using a dual-headed gamma camera. Postischemic hyperperfusion was visually assessed using the early images alone and then using both the super-early and early images, and the frequency of postischemic hyperperfusion and the confidence level of the judgement were evaluated. For quantitative evaluation of image contrast, the contrast ratios (the count ratios of the hyperperfused to normal areas) were calculated. The frequency of postischemic hyperperfusion was significantly higher using both the super-early and early images (28/67 patients) than using the early images alone (17/67 patients, p
Databáze: OpenAIRE
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