Zeitliche Veränderungen von Diffusionskoeffizienten beim Schlaganfall
| Autor: | Horst Urbach, H. H. Schild, Frank Träber, Wolfgang Block, Alexander Hartmann, J Gieseke, Sebastian Flacke, Ewald Keller |
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| Rok vydání: | 2008 |
| Předmět: |
Diagnostic information
medicine.medical_specialty business.industry Combined use medicine.disease Surgery Central nervous system disease Region of interest analysis medicine Effective diffusion coefficient Radiology Nuclear Medicine and imaging business Nuclear medicine Stroke Diffusion MRI Medical systems |
| Zdroj: | RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren. 170:290-297 |
| ISSN: | 1438-9010 1438-9029 |
| DOI: | 10.1055/s-2007-1011042 |
| Popis: | PURPOSE Analysis of temporal changes of ADC values at different stages after stroke. MATERIALS AND METHODS The original images of all scans were evaluated and a region of interest analysis was performed on ADC (apparent diffusion coefficient) maps. 92 patients with symptoms of ischemic stroke were examined at 1.5 Tesla (ACS-NT, Philips Medical Systems). The study protocol included a navigated multishot SE-EPI DWI (b = 0, 189, 750 s/mm-2, TE = 120/140 ms, delta/delta = 49/60 ms), a GraSE (TR/TE = 3500/90 ms) and a FLAIR-TSE (TR/TE/TI = 6000/150/2000 ms) sequence. 8 patients had regular follow-ups. All patients had an additional CT scan. RESULTS In hyperacute stroke ( 3 weeks, n = 20). The combined use of DWI and conventional MRI improved the diagnostic information in 16% of all MR examination beyond the hyperacute assessment. CONCLUSION By means of the ADC-values the age of stroke can be determined. Infarcts at different stages can be readily diagnosed with the combined use of DWI, FLAIR-TSE and GraSE. Pitfalls of DWI and conventional imaging can be avoided. |
| Databáze: | OpenAIRE |
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