Lichen planopilaris after imiquimod 5% cream for multiple BCC in basal cell naevus syndrome
| Autor: | Elvira Moscarella, Caterina Longo, Aimilios Lallas, Giuseppe Argenziano, Alessandra Drummond, Janine Pichler, Iris Zalaudek, Simonetta Piana |
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| Rok vydání: | 2014 |
| Předmět: |
medicine.medical_specialty
Pathology integumentary system Exacerbation business.industry Genetic disorder Imiquimod Basal cell naevus syndrome Dermatology Vitiligo medicine.disease Lichen planopilaris medicine.anatomical_structure Scalp Psoriasis medicine skin and connective tissue diseases business medicine.drug |
| Zdroj: | Australasian Journal of Dermatology. 56:e105-e107 |
| ISSN: | 0004-8380 |
| DOI: | 10.1111/ajd.12151 |
| Popis: | Basal cell naevus syndrome is an inherited autosomal dominant genetic disorder characterised by multiple basal cell carcinomas (BCC), skeletal, neurological and opthalmological abnormalities. The treatment of choice of the often multiple and large BCC consists of a combined approach including surgery, liquid nitrogen and other topical treatment modalities. Imiquimod 5% cream is an immune-response-modifying drug with antiviral and anti-tumour activity. Recent reports have associated the immune-stimulant properties of imiquimod with the exacerbation of several autoimmune skin diseases, such as eczema, psoriasis, vitiligo and lichenoid dermatitis. Here we report a patient with basal cell naevus syndrome who developed a lichen planopilaris on the same site of the scalp, which had been previously treated with two cycles of imiquimod for multiple BCC. |
| Databáze: | OpenAIRE |
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