The Cytogenetic Effects of Logran on Human Lymphocyte Culture

Autor:	Fulya Dilek Gökalp Muranli, Fisun Kaymak
Rok vydání:	2004
Předmět:	Human lymphocyte Mitotic index Cell Biology Plant Science Pharmacology Biology In vitro Peripheral blood Clastogen Immunology Genetics Cytotoxic T cell Lymphocyte culture Animal Science and Zoology
Zdroj:	CYTOLOGIA. 69:467-473
ISSN:	1348-7019 0011-4545
DOI:	10.1508/cytologia.69.467
Popis:	In this study, the cytogenetic effects of a sulphonylurea group herbicide Logran (effective substance; Triasulfuron) were investigated in human peripheral blood lymphocyte culture. The cultures were treated with 2, 4, 8, 16, 32, 64, 128, and 256 μg/ml concentrations of Logran for 24 and 48 h. This compound increased chromosome aberrations (CA) in human lymphocyte culture. Logran decreased Mitotic Index (MI) related to the concentrations. Between the concentrations of 16 and 256 μg/ml Logran, this herbicide is cytotoxic and clastogenic in human peripheral blood lymphocyte culture treated in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26eaebc24bdbd05832a4f15d67f24331 https://doi.org/10.1508/cytologia.69.467 Zobrazit plný text záznamu