Efficient Synthesis of 4-Phenyl-4H-pyran Derivatives via a DIPEA-catalyzed One-Pot Three-Component Reaction

Autor:	Li Jie, Shi-yu Hu, Ye Chen, Ju Liu, Li Jun
Rok vydání:	2019
Předmět:	Reaction conditions Ethanol 010405 organic chemistry Component (thermodynamics) Organic Chemistry Condensation 01 natural sciences Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound chemistry Pyran Yield (chemistry) Malononitrile
Zdroj:	Russian Journal of Organic Chemistry. 55:1791-1799
ISSN:	1608-3393 1070-4280
DOI:	10.1134/s107042801911023x
Popis:	A novel one-pot approach has been developed for a high-yield synthesis of 4-phenyl-4H-pyran derivatives by the three-component condensation of dimethyl 3-oxopentanedioate or 3-oxo-3-arylpropanoic acid esters, aldehydes, with malononitrile in the presence of a DIPEA catalyst in ethanol at room temperature. The significant features of the present strategy include efficiency, high yield, inexpensive catalyst, mild reaction conditions, and simple purification procedure.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26e71684c962bcccc463f4a983ef0f69 https://doi.org/10.1134/s107042801911023x Zobrazit plný text záznamu Plný text ve formátu PDF