NREM-sleep Associated Epileptiform Discharges Disappeared Following a Shift toward the Paleolithic Ketogenic Diet in a Child with Extensive Cortical Malformation
| Autor: | Csaba D. Tóth, Anna Kelemen, Zsófia Clemens |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
Vitamin
medicine.medical_specialty Pediatrics business.industry medicine.medical_treatment Urinary system medicine.disease medicine.disease_cause Sleep in non-human animals Non-rapid eye movement sleep Epilepsy chemistry.chemical_compound Endocrinology chemistry Internal medicine medicine General Earth and Planetary Sciences Effective treatment Paleolithic diet business General Environmental Science Ketogenic diet |
| Zdroj: | American Journal of Medical Case Reports. 3:212-215 |
| ISSN: | 2374-2151 |
| DOI: | 10.12691/ajmcr-3-7-8 |
| Popis: | Purpose: Although the classical ketogenic diet is an effective treatment in childhood epilepsy, it is difficult to maintain on the long term due to side-effects and dislike. Methods: Here we report a case of a child with frequent epileptiform discharges confined to non-rapid-eye-movement (NREM) sleep and extensive cortical malformation. The child was started on a modified version of the classical ketogenic diet we refer to as the paleolithic ketogenic diet. Results: Subsequent follow-up electroencephalograms showed complete normalization of brain electric activity along with cognitive improvement. Neither antiepileptic medication nor vitamin supplements were used. The child strongly adhered to the diet as assessed by regular urinary ketone tests and laboratory work ups. Currently she is on the diet for 17 months. Neither side effects nor clinical signs of nutrient deficiency were observed. Conclusion: We conclude that the paleolithic ketogenic diet was effective, safe and feasible in this case. |
| Databáze: | OpenAIRE |
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