The effect of carnitine on respiration of mitochondria obtained from newborn and adult human subcutaneous white adipose tissue

Autor:	D. Alzamora, Ellen F. Monkus, M. Novak, V. Pardo, Peter Hahn
Rok vydání:	1974
Předmět:	medicine.medical_specialty Adipose tissue macrophages Adipose tissue chemistry.chemical_element White adipose tissue Mitochondrion Biochemistry Oxygen Endocrinology chemistry Internal medicine Respiration medicine Carnitine Beta oxidation medicine.drug
Zdroj:	International Journal of Biochemistry. 5:223-234
ISSN:	0020-711X
Popis:	1. 1. Carnitine added to mitochondria isolated from human newborn white adipose tissue by a new method enhances oxygen consumption, while deoxycarnitine inhibits it. 2. 2. These effects are not seen in adult tissue. 3. 3. Isolated adipose tissue cells from the newborn can be separated into large and small cells. Mitochondria isolated from the former are insensitive to carnitine, while mitochondria isolated from the small cells show increased oxygen consumption on addition of carnitine. 4. 5. It is suggested that these small cells may produce heat by fatty acid oxidation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26ce0987d71b0db12837cff8df7583c6 https://doi.org/10.1016/0020-711x(74)90154-2 Zobrazit plný text záznamu