Synthesis of Chiral γ-Amino-β-hydroxyphosphonate Derivatives from Unsaturated Phosphonates

Autor:	Tsutomu Yokomatsu, Keiichi Fujii, Takehiro Yamagishi, Shiroshi Shibuya
Rok vydání:	2004
Předmět:	Chemistry Dihydroxylation Phosphorus Organic Chemistry Enantioselective synthesis medicine Regioselectivity Organic chemistry chemistry.chemical_element Carnitine Amination medicine.drug
Zdroj:	Synlett. 2004:2505-2508
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-2004-834792
Popis:	γ-Amino-β-hydroxyphosphonates, useful intermediates for the synthesis of phosphonic acid analogues of carnitine, were prepared as their protected derivatives in an enantioselective manner from β,γ-unsaturated phosphonatesthrough asymmetric dihydroxylation and subsequent regioselective amination via the cyclic sulfates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26c81965979ccf32a4b1f384e7adab52 https://doi.org/10.1055/s-2004-834792 Zobrazit plný text záznamu