Vitamin E correlates inversely with non-transferrin-bound iron in sickle cell disease
Autor: | J. D. Phillips, C. Rea, R. Beresford, D. Wheelwright, Andrew D. Blann, Jason T. Wright, David Bareford, S S Marwah |
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Rok vydání: | 2001 |
Předmět: |
chemistry.chemical_classification
Hemolytic anemia medicine.medical_specialty Antioxidant business.industry medicine.medical_treatment Vitamin E Hematology Bleomycin medicine.disease Sickle cell anemia Pathophysiology chemistry.chemical_compound Endocrinology Hemoglobinopathy chemistry Transferrin Internal medicine Immunology Medicine business |
Zdroj: | British Journal of Haematology. 114:917-919 |
ISSN: | 0007-1048 |
DOI: | 10.1046/j.1365-2141.2001.03018.x |
Popis: | Decreased serum vitamin E levels are found in homozygous sickle cell disease (SCD). Excessive transfusions may lead high non-transferrin-bound iron (NTBI). Hypothesizing a relationship between the two, vitamin E (measured using high performance liquid chromatography) was significantly lower in 30 SCD patients than in 30 age-/sex-matched controls (P |
Databáze: | OpenAIRE |
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