Toxicity Status of Nano Powder of Stem Bark of Bauhinia Variegata Linn. on Experimental Animals

Autor:	Prachi Vishwakarma, Shailesh V. Deshpande, Snigdha Das Mandal
Rok vydání:	2023
Předmět:	Pharmacology
Zdroj:	Journal of Natural Remedies. :263-270
ISSN:	2320-3358 0972-5547
DOI:	10.18311/jnr/2023/29566
Popis:	The assumption that medicinal plants are less toxic or cause fewer adverse effects due to their natural composition is debatable. Hence, this study was conducted to evaluate the safety and toxicity of Nano Kanchanara stem bark powder (NKSP) on liver function. The oral acute toxicity of NKSP was conducted in accordance with OECD Guidelines 423 and was carried out with six (6) female Wistar albino rats, divided into two groups of three rats each. Test rats were orally administered a single dose of 2000 mg/kg of NKSP and were observed for changes in behavior and mortality for the next 14 days, while the Control Group was given feed and water ad libitum. The data obtained from the oral acute toxicity study indicated that there were non-significant (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26bd11cd4ca37dca0b73b714a76a8d5d https://doi.org/10.18311/jnr/2023/29566 Zobrazit plný text záznamu