| Autor: |
Stanley S. Grant, Elizabeth Donnelly, Jean E. Cruikshank, Michael W. Varner, Dwight P. Cruikshank |
| Rok vydání: |
1983 |
| Předmět: |
|
| Zdroj: |
American Journal of Obstetrics and Gynecology. 146:204-211 |
| ISSN: |
0002-9378 |
| Popis: |
Maternal, fetal, and neonatal results and complications were analyzed after 923 genetic amniocenteses. Maternal age of 35 years and beyond was associated with a 2.0% risk of fetal trisomy 21 and a 3.0% risk of all major chromosome abnormalities. Comparable rates for women aged 40 and beyond were 4.8% and 7.2%. Neural tube defects were detected in 0.15% of procedures done for maternal age and 3.4% of those done for a previous involved child. The risk of spontaneous abortion as a result of amniocentesis was 0.2% to 1.4%. Mahogany or green fluid was associated with a 29% rate of fetal loss. Unexplained midtrimester elevations of maternal serum α-fetoprotein were associated with a 38% risk of a subsequent low-birth weight infant. The only neonatal complication associated with amniocentesis was an apparent marked increase in the incidence of lower-extremity orthopedic abnormalities. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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