Management of chemotherapy‐induced anemia (CIA) with biosimilar epoetin alfa (Binocrit) in patients with pancreatic cancer (PC): An interim analysis of an ongoing French national observational study (The OncoBOS study)

Autor: Jean Philippe Metges, Gilles Boschetti, Sophie Nahon, Daniela Petran, Jean-Pierre Crumbach, Jérôme Desramé, Otilia Stamerra, Camille Aubron-Olivier, Vincent Boulanger, Domitille Fernet
Rok vydání: 2015
Předmět:
Zdroj: Journal of Clinical Oncology. 33:479-479
ISSN: 1527-7755
0732-183X
DOI: 10.1200/jco.2015.33.3_suppl.479
Popis: 479 Background: OncoBOS is a prospective, non-interventional study describing Binocrit use in routine practice in France in patients receiving chemotherapy treatment (CT) for solid tumors, lymphoma or myeloma. This interim sub-analysis focuses on patients with PC. Methods: Patients ≥18 years with PC, CIA and eligible for treatment with Binocrit were included in this analysis. Patients characteristics, data on CIA and its management and predominant factors considered by the physician in prescribing Binocrit were recorded at baseline (BL), 3-4 weeks and 12 (± 1) weeks later. Hemoglobin (Hb) outcomes assessed included the proportion of patients achieving a Hb increase ≥1 and ≥2 g/dL, and the mean Hb change from BL. Results: 59 patients with PC (32 females (54.2%), mean age 68.3 years) from 22 sites were recruited from September 2011 to April 2014. Mean and median BL Hb levels were both 10 g/dL. The mean increase in Hb level was 1.1 g/dL after 1 month and 1.2 g/dL after 3 months (p
Databáze: OpenAIRE