Synthesis of (4-arylpyrrolidin-2-ylidene) derivatives of cyclic β-dicarbonyl compounds from cinnamoyl precursors

Autor:	Valerii F. Traven, F. S. Pashkovskii, A. M. Borunov, Fedor A. Lakhvich, Yu. S. Dontsu, Dmitry B. Rubinov
Rok vydání:	2014
Předmět:	chemistry.chemical_compound Nitromethane chemistry Stereochemistry Yield (chemistry) Organic Chemistry Nitro Michael reaction Enone
Zdroj:	Russian Journal of Organic Chemistry. 50:1598-1612
ISSN:	1608-3393 1070-4280
Popis:	1,4-Conjugate Michael addition of nitromethane to the enone fragment of cinnamoyl derivatives of carbo- and heterocyclic β-dicarbonyl compounds provided the corresponding nitromethyl derivatives. The chemoselective reduction of the nitro group in the latter afforded 4-arylpyrrolidin-2-ylidene derivatives of β-dicarbonyl compounds in high yield. The reaction products with the heterocyclic β-dicarbonyl fragment are formed as equilibrium mixture of E- and Z-rotamers in which the E-rotamer predominates.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::26624c5315b4c0aeab255fc28f9c0050 https://doi.org/10.1134/s1070428014110116 Zobrazit plný text záznamu Plný text ve formátu PDF