NIR-excited upconversion nanoparticles used for targeted inhibition of Aβ42 monomers and disassembly of Aβ42 fibrils

Autor: Yijia Guan, Weijie Cao, Tao Li, Jieyi Qin, Qilong He, Xiaofeng Jia, Yuqing Li, Yuhua Zhang, Jianguo Liao
Rok vydání: 2023
Předmět:
Zdroj: Journal of Materials Chemistry B. 11:1445-1455
ISSN: 2050-7518
2050-750X
DOI: 10.1039/d2tb02104h
Popis: Herein, we designed and constructed functional upconversion nanoparticles (UCNPs@SiO2-ThS), which can not only inhibit the aggregation of Aβ42 monomers, but also disassemble Aβ42 fibrils under the irradiation of near-infrared (NIR) light.
Databáze: OpenAIRE