POLYPHARMACY IN ELDERLY STROKE PATIENTS: AN OBSERVATIONAL AND INTERVENTIONAL STUDY IN A PORTUGUESE STROKE UNIT

Autor: David Fortes, Joao Boavida, Mariana Fonseca, Teresa Fonseca, Luis Mieiro, Marco Narciso
Rok vydání: 2011
Předmět:
Zdroj: European Journal of Internal Medicine. 22:S62
ISSN: 0953-6205
DOI: 10.1016/s0953-6205(11)60254-9
Popis: Background: Portugal’s population is ageing. High comorbidity and polypharmacy are associated to increased age. Although controversial, most authors define polypharmacy as 6 or more prescribed drugs. Polypharmacy represents increased risk of interaction and side-effects. Stroke is a critical event that demands review of long-term medication. To our knowledge, this is the first study to analyze the profile of highly medicated stroke patients. Methods: Observational study of routinely collected data over a 6-month period in a Stroke Unit of an Internal Medicine Department. Statistical analysis with T-test and chi-square test was performed. Results: 89 consecutive acute stroke patients reported during this period. Mean age 75.5±11.5 years, 59.6% women and 55.1% of patients had 6 or more drugs before admission. We found that polypharmacy patients were older (80.3±8.8 vs 69.7±11.9, p
Databáze: OpenAIRE