Chemiluminescence study of the contents of the products of Cu2+-induced lipid peroxidation in different fractions of human blood lipoproteins
| Autor: | Dremina Es, Vakhrusheva Tv, Victor S. Sharov, Azizova Oa, Yu. A. Vladimirov |
|---|---|
| Rok vydání: | 1995 |
| Předmět: |
inorganic chemicals
Chromatography Human blood Chemistry Kinetics High density General Medicine General Biochemistry Genetics and Molecular Biology law.invention Lipid peroxidation chemistry.chemical_compound Diene conjugate Biochemistry law lipids (amino acids peptides and proteins) Incubation Chemiluminescence Lipoprotein |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 119:135-139 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | It is demonstrated that the content of the primary products of lipid peroxidation reaches the maximum after about 1-h incubation with Cu2+ and then declines. At a Cu2+ concentration of about 10–15 μM, the content of lipid peroxidation products is maximal; it does not rise with a further increase in the Cu2+ concentration. Comparison of the kinetics of lipid peroxidation in different lipoprotein fractions shows that low density lipoproteins are much more strongly oxidized than high density lipoproteins. A strong positive correlation between the amplitude of the chemiluminescence burst and the diene conjugate content is established in 79 independent measurements. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink