Biological Safety Assessment of a Colored Zirconia Ceramic: Hemolysis and Short-Term Systemic Toxicity Tests

Autor: Bin Deng, Huai Xiu Lu, Ning Wen, Jie Liu, Yuan Fu Yi, Longquan Shao, Wei Wei Zhang
Rok vydání: 2011
Předmět:
Zdroj: Key Engineering Materials. 492:505-508
ISSN: 1662-9795
DOI: 10.4028/www.scientific.net/kem.492.505
Popis: Objective: To evaluate the biological safety of a colored zirconia ceramic regarding its hemolytic activity and short-term systemic toxicity. Methods: Fresh anti-coagulating rabbit blood was mixed with test materials and the hemolytic activities detected spectrophotometrically. Suspensions of the ceramic were fed to rats for one week while monitoring food consumption and relative growth rate and with subsequent pathology examinations of vital organs and tissues. Results: The hemolytic activity of the ceramics was
Databáze: OpenAIRE