Early Cognitive Domain Deficits in Patients with Aneurysmal Subarachnoid Hemorrhage Correlate with Functional Status

Autor: Sandy Wai Lam, Vincent Mok, Adrian Wong, Wai Sang Poon, Karine Ngai, George K.C. Wong
Rok vydání: 2016
Předmět:
Zdroj: Acta Neurochirurgica Supplement ISBN: 9783319225326
DOI: 10.1007/978-3-319-22533-3_26
Popis: Objective: Cognitive deficits commonly occur after aneurysmal subarachnoid hemorrhage (aSAH), although a few studies systemically evaluate its early impact. We hypothesized that early cognitive domain deficits in patients with aSAH correlate with functional status. Methods: We carried out a prospective observational study in Hong Kong, for which patients with aSAH, aged 21–75 years, who had been admitted within 96 h of ictus were recruited. The cognitive assessment used was the domain-specific neuropsychological assessment battery at 2–4 weeks (n = 74) after ictus. Functional status was measured using the modified Rankin Scale (mRS) and the Lawton Instrumental Activity of Daily Living (IADL) scale. The study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193). Results: Unfavorable outcome (mRS 3–5) was associated with visuospatial memory domain deficit and language domain deficit. Dependent IADL (score
Databáze: OpenAIRE