Novel One-Pot Cyclization of the Blaise Reaction Intermediate and Arylglyoxals: The Synthesis of Substituted NH-Pyrroles

Autor:	Zhiwei Chen, Xiaofeng Yang, Xiangqing Chang, Hao Chen
Rok vydání:	2017
Předmět:	chemistry.chemical_compound Tandem Nitrile 010405 organic chemistry Chemistry Reagent Organic Chemistry Blaise reaction Organic chemistry 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Synlett. 28:1463-1466
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-0036-1588168
Popis:	A novel tandem Blaise reaction for the one-pot synthesis of substituted NH-pyrroles was described. The Blaise reaction intermediate, generated in situ from Reformatsky reagent and nitrile, reacted with arylglyoxals chemoselectively to afford a wide variety of substituted NH-pyrroles in good yields.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::261a29ea1b355e7677a8050cf0638fd7 https://doi.org/10.1055/s-0036-1588168 Zobrazit plný text záznamu