Chemoselective and Catalytic Trimethylsilylation of Alcohols and Phenols by 1,1,1,3,3,3-Hexamethyldisilazane and Catalytic Amounts of PhMe3N+Br3−

Autor:	Nasrin Cheraghi-Fathabad, Arash Ghorbani-Choghamarani
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Chemistry Phenyltrimethylammonium tribromide Organic chemistry Phenol Alcohol General Medicine Phenols Catalysis Dichloromethane
Zdroj:	Chinese Journal of Catalysis. 31:1103-1106
ISSN:	1872-2067
DOI:	10.1016/s1872-2067(10)60107-6
Popis:	An efficient procedure for the trimethylsilylation of alcohols and phenols is presented. The combination of 1,1,1,3,3,3-hexamethyldisilazane and a catalytic amount of phenyltrimethylammonium tribromide (PhMe 3 N + Br 3 − ) was found to be effective for the trimethylsilylation of alcohols and phenols. The protection reaction is very simple and homogenously performed in dichloromethane at room temperature and mild conditions.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::260a2ebb1ef38860943ae7266859e12b https://doi.org/10.1016/s1872-2067(10)60107-6 Zobrazit plný text záznamu Full Text from ScienceDirect