Peptide modification by incorporation of α-trifluoromethyl α-amino acids via trifluoromethyl-substituted acylimines

Autor: Klaus Burger, Martin Rudolph, E. Höss, L. Seymour, Christian Schierlinger
Rok vydání: 1993
Předmět:
Zdroj: Journal of Fluorine Chemistry. 61:163-170
ISSN: 0022-1139
DOI: 10.1016/s0022-1139(00)80427-3
Popis: α-Trifluoromethyl-substituted α-amino acids can be introduced into the C-terminal position of peptides via acylimines obtained on reaction of trifluoropyruvates with N-protected α-amino acid amides and dipeptide amides, respectively.
Databáze: OpenAIRE