Transfer of Low Nanoliter Volumes between Microplates Using Focused Acoustics—Automation Considerations

Autor: Richard Ellson, Mitchell Mutz, Brent Browning, Lawrence Lee, Michael F. Miller, Roeland Papen
Rok vydání: 2003
Předmět:
Zdroj: JALA: Journal of the Association for Laboratory Automation. 8:29-34
ISSN: 1535-5535
DOI: 10.1016/s1535-5535-03-00011-x
Popis: Acoustic droplet ejection (ADE) gently and precisely aliquots nanoliter and picoliter liquid volumes without any physical contact with the solution being transferred. The technology is very automation-friendly, as it is compatible with conventional microplates. Focused energy from an acoustic transducer induces droplet ejection into an inverted standard microplate. The commercial system transfers low-nanoliter volumes of dimethyl sulfoxide–dissolved compound libraries and thereby enables cell-based assays to be performed in 1536-well plates.
Databáze: OpenAIRE