Impact of consanguinity on spontaneous pregnancy loss and descendants’ health in north Morocco

Autor: Houria Hardouz, Amine Arfaoui, Ali Quyou
Rok vydání: 2023
Předmět:
Zdroj: Arab Gulf Journal of Scientific Research.
ISSN: 2536-0051
1985-9899
DOI: 10.1108/agjsr-01-2023-0027
Popis: PurposeThe present study aims to bring out the impact of consanguinity on spontaneous pregnancy loss (SPL) and on descendants’ health, among the population of north Morocco.Design/methodology/approachConvenience sampling was used for collecting data. A questionnaire was randomly administered to 385 couples represented by either the husband, the wife or both. The study lasted for three months, from January to March 2015.FindingsIn total, 238 valid questionnaires were analysed. The results showed that the consanguinity rate was 45.23% and that most consanguineous unions were between first cousins (91%). Data analysis revealed that SPL risk was similar in consanguineous and non-consanguineous couples (OR = 1.6; IC95% = 0.9–2.9). Also, no significant difference was observed in terms of SPL type (OR = 1.6; IC95% = 0.7–3.9) and frequency (p = 0.81). However, late SPL frequency was significantly lower in consanguineous couples (p p = 0.73). On the other hand, consanguineous couples displayed a significantly higher risk of descendants’ health disorders in comparison with non-consanguineous ones. Moreover, the consanguineous couples had a significantly higher number of children with health disorders (p Originality/valueThe population awareness regarding the negative effects of consanguinity should be raised through education programmes and premarital, prenatal and genetic counselling services.
Databáze: OpenAIRE