Myocardial reactive hyperemia caused by initial myocardial anoxia during aortic valve replacement
| Autor: | Lauri S. Nuutinen, Pentti Kärkölä, S. Tuononen, Matti I. Kairaluoma, Erkki Saarela, Risto Pokela, Teuvo K. I. Larmi |
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| Rok vydání: | 1978 |
| Předmět: |
inorganic chemicals
Pulmonary and Respiratory Medicine medicine.medical_specialty business.industry Blood flow musculoskeletal system medicine.disease Collateral circulation environment and public health carbohydrates (lipids) Coronary arteries medicine.anatomical_structure Aortic valve replacement Internal medicine Long period medicine Cardiology Surgery Hyperemic response Cardiology and Cardiovascular Medicine business Reactive hyperemia Artery |
| Zdroj: | The Journal of Thoracic and Cardiovascular Surgery. 75:716-721 |
| ISSN: | 0022-5223 |
| DOI: | 10.1016/s0022-5223(19)41319-6 |
| Popis: | Reactive hyperemic response of individual coronary arteries and of the whole heart to anoxia during coronary cannulation was investigated in 10 patients undergoing aortic valve replacement. Reactive hyperemic response in man is identical to that reported in experimental investigations. The duration of hyperemic response was dependent on the length of the preceding period of anoxia; the longer the period of anoxia, the more prolonged was the hyperemic response. No significant collateral circulation between the coronary arteries could be demonstrated during prolonged anoxia of an individual coronary artery. Blood flow debt was almost always overpaid, but the repayment percentage decreased with the lengthening of the anoxic period, being 460 percent after a short period of anoxia (2 minutes), 230 percent after an anoxic period of moderate length (3 to 5 minutes), and only 160 percent after a long period of anoxia (7 minutes). The total mean repayment of blood flow debt of the whole heart was 195 percent. |
| Databáze: | OpenAIRE |
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