A Computer Aided Investigation on Strain Movements in Compacts Under Constant Stress Within the Die

Autor:	T. C. Buttery, D. N. Travers, Metin Celik
Rok vydání:	1983
Předmět:	Pharmacology Materials science business.product_category Consolidation (soil) Strain (chemistry) Organic Chemistry Pharmaceutical Science Stress (mechanics) Constant stress Drug Discovery Die (manufacturing) Composite material business Avicel PH-101 Holding time
Zdroj:	Drug Development and Industrial Pharmacy. 9:139-157
ISSN:	1520-5762 0363-9045
DOI:	10.3109/03639048309048550
Popis:	A 2.54cm diameter punch and die set has been used in conjunction with a Mayes Hydraulic Machine to examine strain movements within the die of compacts maintained at constant stress. These were prepared from the bases Avicel PH 101 (AV), Sta-Rx 1500 (ST), Paracetamol DC (PC), Emdex (ED) and Eacompress (EC).Compression force and punch movements were simultaneously monitored using a CBM nicroconputer with disk storage of data.All compacts showed time dependent consolidation under constar. stress when held at ‘holding time’ of up to 60s. PC, AV and ST exhibited comparable movements but that of ED and EC ware less.Elastic recovery on sudden release of load was followed using machine code logging over a period of 90ms. Large recoveries were recorded for AV, PC and ST. If load release was immediate (zero holding time) then the recovery was greater when compared with recovery after holding tines of 30 and 60s, suggesting that some elastic energy was dissipated during the holding time. Elastic recovery of ...
Databáze:	OpenAIRE
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