Mitogens induced regulation of sea star axial organ cell humoral immune response in vitro

Autor:	Gilles Luquet, C. Brillouet, Michel Leclerc
Rok vydání:	1986
Předmět:	biology Asterias Cell Cell Biology biology.organism_classification In vitro Cell biology In vitro stimulation Immune system medicine.anatomical_structure In vivo Immunology medicine biology.protein Anamnestic response Antibody
Zdroj:	Cell Biology International Reports. 10:667-675
ISSN:	0309-1651
DOI:	10.1016/0309-1651(86)90144-x
Popis:	A specific anamnestic response occurs in the sea star, Asterias rubens after in vivo and in vitro stimulation of axial organ cells, with hapten-carrier conjugates. The effect of the mitogenic lectin Con.A on the in vitro production of antibody like factors is studied by means of a haemolytic assay. It appears that Con.A produces a modulating effect on the secondary in vitro response of sea star axial organ cells. I.O-Methyl-α-D-Mannopyranoside inhibits the modulating effect of Con.A in controls. On the other hand it appears clearly that LPS has no action on the synthesis and/or the activity of the “antibody-like” factors secreted by axial organ cells.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::25a1871e82c221806af552db53303d9f https://doi.org/10.1016/0309-1651(86)90144-x Zobrazit plný text záznamu