| Autor: |
Patrick L. Mollison, I. Maureen Young |
| Rok vydání: |
1941 |
| Předmět: |
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| Zdroj: |
Quarterly Journal of Experimental Physiology and Cognate Medical Sciences. 30:313-327 |
| ISSN: |
0033-5541 |
| DOI: |
10.1113/expphysiol.1941.sp000841 |
| Popis: |
Twenty patients have received 26 transfusions of stored blood, and the fate of the erythrocytes of the donor followed quantitatively by differential agglutination. A method of performing control agglutinations using the sera both of the ABO and MN systems is suggested. A further application of differential agglutination is outlined. Its purpose is the following of the fate of two transfusions given simultaneously. This method has been used for (1) comparison of methods of storage; (2) to obtain a comparison of the survival of two different “ages” of blood in the same patient. 1. A high proportion of the erythrocytes of blood stored in citratesaline-glucose survive transfusion. Furthermore, the total time of survival is little inferior to that of fresh blood. 2. These observations suggest that the present method of storage is good and that little more than the normal ageing process occurs at least in blood stored for 18 days or less. In connection with Ashby's work on the survival of the transfused erythrocytes of fresh blood, P. E. Weil [1940] has remarked: “Ce n'est donc pas aux depens de l'haemoglobine des globules detruits que l'organisme trouve le possibilite de former des nouveaux globules, mais ce sont bien les globules transfuses eux-meme qui continuent leur vie et leurs fonctions physiologiques.” These words might be used as a refutation of the remarks quoted at the beginning of this paper. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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