2,6-Disubstituted 4-azidopyrimidines: synthesis, kinetic and thermodynamic studies of azide-tetrazole rearrangement by NMR spectroscopy
| Autor: | Viktor P. Krivopalov, Elena B. Nikolaenkova, V. I. Mamatyuk, N. V. Pleshkova |
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| Rok vydání: | 2017 |
| Předmět: |
010405 organic chemistry
General Chemistry Nuclear magnetic resonance spectroscopy 010402 general chemistry Kinetic energy 01 natural sciences Tautomer 0104 chemical sciences Solvent chemistry.chemical_compound chemistry Computational chemistry Tetrazole Azide Two-dimensional nuclear magnetic resonance spectroscopy Electronic properties |
| Zdroj: | Russian Chemical Bulletin. 66:2095-2102 |
| ISSN: | 1573-9171 1066-5285 |
| DOI: | 10.1007/s11172-017-1986-2 |
| Popis: | Thermodynamic and kinetic parameters of the tautomeric tetrazole-azide rearrangement for a series of 2,6-disubstituted 4-azidopyrimidines are determined by NOESY/EXSY and DNMR: ΔH = 15—28 kJ mol–1; ΔS = 47—65 J mol–1 К–1; Е a = 93—117 kJ mol–1; lgA = 15.1—18.9. They are dependent on electronic properties of the substituents and the polarity of solvent. |
| Databáze: | OpenAIRE |
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