A study of renal dysfunction among HIV-infected patients on tenofovir based ART regimen in the Northeast part of India

Autor:	Sudhangshu Mazumdar, Lourembam Gayatri, Nang Neeta Manpang, Dhanaraj Singh Chongtham, Duyu Nobing, M. Bijoy Singh
Rok vydání:	2020
Předmět:	medicine.medical_specialty Creatinine Tenofovir medicine.diagnostic_test business.industry virus diseases Renal function Physical examination Nephrotoxicity Regimen chemistry.chemical_compound chemistry Internal medicine medicine Underweight medicine.symptom business medicine.drug Cohort study
Zdroj:	International Journal of Advances in Medicine. 7:1227
ISSN:	2349-3933 2349-3925
DOI:	10.18203/2349-3933.ijam20203075
Popis:	Background: Tenofovir is an integral part of the currently used antiretroviral therapy (ART) regime. However, nephrotoxicity has been a concern. This study has been undertaken to evaluate the prevalence and risk factors of renal dysfunction among HIV-patients on tenofovir containing ART regime.Methods: This cohort study was conducted at Regional Institute of Medical Sciences. HIV-patients newly started on tenofovir containing ART regime were subjected to detailed history, thorough physical examination, and routine investigations. Serum creatinine levels and creatinine clearance were measured at regular intervals.Results: Mean age of the patients was 42.37±10.8 years. Most of the patients had normal BMI (66%) and 22% were obese while 12% of the cases were underweight. Majority of the patients had CD4 count less than 350 cells/cumm. Renal dysfunction, defined as creatinine clearance
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::25783a512a1ca5fb59502d4b5c170476 https://doi.org/10.18203/2349-3933.ijam20203075 Zobrazit plný text záznamu