Exploration on significance of platelet cd62p, cdp63 determination in type 2 diabetes mellitus patients with blood stasis syndrome

Autor:	Wanjia Xing, Tianqin Kou, Geping Yin, Hui Yan, Shenglan Zhang, Zhaoshun Jiang
Rok vydání:	2000
Předmět:	medicine.medical_specialty CD63 business.industry Type 2 Diabetes Mellitus General Medicine Blood stasis Blood flow Positive correlation Gastroenterology Endocrinology Internal medicine medicine Platelet sense organs Platelet activation business Syndrome differentiation
Zdroj:	Chinese Journal of Integrated Traditional and Western Medicine. 6:22-24
ISSN:	1006-6497
DOI:	10.1007/bf02973141
Popis:	Objective: To study the relationship between blood stasis syndrome (BSS) and platelet activation and its influencing factors in type 2 diabetic mellitus (DM).Methods: Platelet CD62p, CD63 expressions were determined in 30 type 2 DM patients with BSS, 27 type 2 DM patients without BSS and 20 normal controls by flow cytometry.Results: CD62p, CD63 levels were significantly higher in type 2 DM group with BSS than those in the type 2 DM group without BSS and in the normal controls. CD62p was positively correlated with CD63, while positive correlation existed between HbA1c, LDL-C and CD62p in DM patients with BSS.Conclusions: The increased level of platelet activation was the primary molecular basis of BSS in type 2 DM. It was important to perform the syndrome differentiation of BSS and treatment of activating blood flow to remove BSS in type 2 DM.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::2570510cf81883ab6da4456e4a74a3d1 https://doi.org/10.1007/bf02973141 Zobrazit plný text záznamu Full text from SpringerLink