| Popis: |
Chicken embryos were first used to study viruses in 1911 by Rous and Murphy (21). However, years elapsed before the use of the embryo was recognized for its great potential in virus research when Woodruff and Goodpasture (34) used chicken embryos to study fowl poxvirus. The early workers did not consider that chicken embryos could carry unwanted organisms, which could compromise the integrity of experiments. In 1946, Beveridge and Burnet (4) stated, "There is no well authenticated report of a chick embryo being a natural carrier of any virus, and the technical problem of preventing entry of unwanted viruses to it is immensely simpler than with any type of free-living animal." |
