Conversion of 2-(trimethylsilyl)ethyl sulfides into thioesters

Autor:	Hans Grundberg, Ulf J. Nilsson, Magnus Andergran
Rok vydání:	1999
Předmět:	Reaction conditions chemistry.chemical_classification chemistry.chemical_compound Trimethylsilyl Chemistry Carboxylic acid Organic Chemistry Drug Discovery medicine Organic chemistry Biochemistry Chloride medicine.drug
Zdroj:	Tetrahedron Letters. 40:1811-1814
ISSN:	0040-4039
DOI:	10.1016/s0040-4039(99)00016-7
Popis:	Treatment of 2-(trimethylsilyl)ethyl sulfides with a carboxylic acid chloride and AgBF 4 in CH 2 Cl 2 furnishes the corresponding thioesters in high yields and purities. The conversion of 2-(trimethylsilyl)ethyl sulfides into synthetically versatile thioesters allows such sulfides to be used as sulfhydryl protective groups, since such sulfides are easily prepared and are stable towards many reaction conditions encountered in organic syntheses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::25624b4e38d9f5310076d9c3ca4c2283 https://doi.org/10.1016/s0040-4039(99)00016-7 Zobrazit plný text záznamu Full Text from ScienceDirect