A comparative study of the components of the antioxidant defense system during growth of the mycelium of a wild-type Neurospora crassa strain and mutants, white collar-1 and white collar-2
| Autor: | Rudchenko Mn, O. A. Leonovich, T A Belozerskaia, Rabinovich IaM, Gessler Nn |
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| Rok vydání: | 2006 |
| Předmět: | |
| Zdroj: | Applied Biochemistry and Microbiology. 42:293-297 |
| ISSN: | 1608-3024 0003-6838 |
| DOI: | 10.1134/s0003683806030136 |
| Popis: | A comparative study of the changes in the components of the antioxidant defense system (ADS), the activity of superoxide dismutase (SOD) and catalase and the level of extractable SH-groups, during the growth of wild-type and mutant (white collar-1 and white colar-2) Neurospora crassa strains was performed. Oxidative stress developing during spore germination and upon the transition to a stationary growth phase was accompanied in all strains by an increase in the level of extractable SH-groups and SOD activity, whereas the total catalase activity decreased during growth. However, in contrast to the wild-type strain, the activity of the catalase in the mutant strains wc-1 and wc-2 slightly increased upon the transition to the stationary phase. In the wc-2 mutant, SOD activity and the level of extractable SH-groups in the exponential growth phase were always lower than in the wild-type and wc-1 strains. The role of wc-1 and wc-2 genes in the level regulation of reactive oxygen species is discussed. |
| Databáze: | OpenAIRE |
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