Isolation and some characteristics of H-2 transplantation antigen in mice

Autor:	V. I. Govallo, M. A. Vladimirskii
Rok vydání:	1970
Předmět:	Spleen Biological activity General Medicine Biology Molecular biology General Biochemistry Genetics and Molecular Biology In vitro Transplantation Isoantibodies medicine.anatomical_structure Antigen Immunity medicine Cytotoxic T cell
Zdroj:	Bulletin of Experimental Biology and Medicine. 70:1411-1413
ISSN:	1573-8221 0007-4888
DOI:	10.1007/bf02066791
Popis:	Details are given of the isolation of H-2 transplantation antigen from the spleen of BALB/c mice in a soluble form. The antigen was identified by exhaustion of the activity of the specific isoantiserum, purified by gel filtration, and its approximate molecular weight determined. The isolated antigen is biologically active and it induces the appearance of specific transplantation immunity, detectable by the secondary response test, and also of humoral isoantibodies detectable by a cytotoxic test in vitro.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::254c28db3add06b0214a99979b363a74 https://doi.org/10.1007/bf02066791 Zobrazit plný text záznamu Full text from SpringerLink