Anti-IL-31 receptor antibody is shown to be a potential therapeutic option for treating itch and dermatitis in mice
| Autor: | N Yamashita, Keiko Kasutani, Hidetomo Kitamura, Etsuko Fujii, S Ohyama, Hideki Adachi, M Hasegawa |
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| Rok vydání: | 2014 |
| Předmět: |
Pharmacology
biology business.industry medicine.medical_treatment Atopic dermatitis medicine.disease Receptor antibody Cytokine immune system diseases Immunology otorhinolaryngologic diseases biology.protein Medicine Itching medicine.symptom Antibody skin and connective tissue diseases business Receptor |
| Zdroj: | British Journal of Pharmacology. |
| ISSN: | 0007-1188 |
| Popis: | Background and Purpose IL-31, which is described as a pruritogenic cytokine, is linked to the itching that is associated with allergic and non-allergic eczema, but the precise pruritogenic mechanism of IL-31 and its potential as a therapeutic target for atopic dermatitis (AD) have not been determined. |
| Databáze: | OpenAIRE |
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