Channel-Type Molecular Structures. Part 2. Synthesis of Bouquet-Shaped Molecules Based on a ?-Cyclodextrin Core
| Autor: | Josette Canceill, Ludovic Jullien, Liliane Lacombe, Jean-Marie Lehn |
|---|---|
| Rok vydání: | 1992 |
| Předmět: |
chemistry.chemical_classification
Cyclodextrin Stereochemistry Organic Chemistry Nuclear magnetic resonance spectroscopy Biochemistry Catalysis Inclusion compound Inorganic Chemistry chemistry.chemical_compound Membrane chemistry Drug Discovery Amphiphile Side chain Molecule Physical and Theoretical Chemistry Lipid bilayer |
| Zdroj: | Helvetica Chimica Acta. 75:791-812 |
| ISSN: | 1522-2675 0018-019X |
| DOI: | 10.1002/hlca.19920750315 |
| Popis: | A new series of channel-type molecules presenting the features of potential transmembrane structures is described. They result from the grafting of amphiphilic side chains on a β-cyclodextrin derivative 3 that constitutes the organizing core. They belong to the ‘bouquet’ family (B). Compounds bearing poly(oxyethylene) side chains, B16 and 17, and their polymethylene analogues B18 and 19, were synthesized. The properties investigated emphasize the suitability of such molecules to be incorporated into lipid bilayer membranes. |
| Databáze: | OpenAIRE |
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