| Autor: |
Michael S. Croft, Carlos Tabarez, Patrick Moyna, Shubhashis Chakrabarty, Guillermo Moyna, Jaime Franco |
| Rok vydání: |
2013 |
| Předmět: |
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| Zdroj: |
Proceedings of the 14th Brazilian Meeting on Organic Synthesis Proceedings. |
| DOI: |
10.5151/chempro-14bmos-r0075-1 |
| Popis: |
Heteroatom-bearing tetracyclic backbones are important scaffolds for a number of biological targets. These compounds have been widely used as antimicrobial and anticancer agents, and include tetracycline antibiotics and topoisomerase inhibitors. 1,2 We have shown that a novel class of tetracyclic tetraindenoquinolines could be obtained through photoisomerization of benzotropolone derivatives. 3 In this presentation we detail the preparation of a series of these compounds as well as the corresponding indenoquinolines (Figure 1), and discuss their biological evaluation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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