A Simple Thin-Layer Chromatographic Fingerprint Method for Distinguishing Between Radix Paeoniae Rubra and Radix Paeoniae Alba

Autor: Liu Yang, Peishan Xie, Shun-Jun Xu, Runtao Tian, Qianru Feng, Hepin Liu
Rok vydání: 2009
Předmět:
Zdroj: Journal of Liquid Chromatography & Related Technologies. 32:2893-2905
ISSN: 1520-572X
1082-6076
Popis: According to different processing methods and growth conditions, the dry roots of Paeonia lactiflora Pallas are generally classified as Radix Paeoniae Alba (Bai-shao) and Radix Paeoniae Rubra (Chi-shao), which have been officially recorded under different monographs in all editions of Chinese Pharmacopoeia. Although deriving from the same plant origin, the two herbs have individual chemical characteristics, which eventually result in their different efficacies. To better understand their clinical effects, it is important to display the similarity and differentiation of entire chemical patterns of the two drugs in detail. In the present study, the high performance thin layer chromatographic fingerprints combining digital scanning profiling were developed using two suites of mobile phases and derivatization reagents for the ‘high polarity component’ and ‘lipophilic component’ fractions contained in the herbal drugs, respectively. The unique properties of the HPTLC fingerprints were validated by ana...
Databáze: OpenAIRE
Nepřihlášeným uživatelům se plný text nezobrazuje