Macrocyclic Platinum(II) Complexes with a Bifunctional Diphosphine Ligand

Autor:	Dirk W. Zant, Jarl Ivar van der Vlugt, Maxime A. Siegler, Daniël L. J. Broere, Andrea E. Pascui, Karlotta van Rees
Rok vydání:	2015
Předmět:	chemistry.chemical_classification Stereochemistry Ligand chemistry.chemical_element Medicinal chemistry Reductive amination Coordination complex Inorganic Chemistry Benzaldehyde chemistry.chemical_compound chemistry Platinum Bifunctional Isomerization Cis–trans isomerism
Zdroj:	European Journal of Inorganic Chemistry. 2015:5687-5693
ISSN:	1099-0682 1434-1948
DOI:	10.1002/ejic.201501055
Popis:	The preparation and coordination chemistry of a ditopic ligand scaffold (1H2), containing both a phosphorus-donor (P) and a nitrogen-donor (N) binding pocket, is reported. The ligand was synthesized by reductive amination from 3-(diphenylphosphino)benzaldehyde and N-(2-aminophenyl)-N-methylbenzene-1,2-diamine. Selective coordination in the P-pocket was achieved for PtII, with careful control over the reaction conditions and precursor materials providing access to either the thermodynamic cis isomer, cis-PtCl2(1H2) (2), or the kinetic trans isomer, trans-PtCl2(1H2) (3). Both species have been fully characterized both in the solid state and in solution. Thermodynamic parameters for isomerization processes of 2 and 3 have been determined. Halide abstraction from 2 and 3 led to formation of cis-[Pt(CH3CN)(Cl)(1H2)]BF4 and trans-[Pt(CH3CN)(Cl)(1H2)]BF4.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::24df76fa126023e7fe49f0ad252d6f91 https://doi.org/10.1002/ejic.201501055 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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