In vitro Effect of sulfonamides plus Urea on Escherichia coli in Presence of Para-aminobenzoic acid
Autor: | Ernest A. Strakosch, Daniel J. Tenenberg, H. M. Tsuchiya, William G. Clark |
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Rok vydání: | 1942 |
Předmět: |
Chromatography
Sodium Sulfonamide (medicine) chemistry.chemical_element Sulfanilamide Bacterial growth medicine.disease_cause General Biochemistry Genetics and Molecular Biology chemistry.chemical_compound Sulfadiazine Sulfathiazole chemistry Biochemistry Urea medicine Escherichia coli medicine.drug |
Zdroj: | Experimental Biology and Medicine. 51:247-249 |
ISSN: | 1535-3699 1535-3702 |
DOI: | 10.3181/00379727-51-13919 |
Popis: | SummaryThe concentrations of sulfanilamide, sodium sulfathiazole and sodium sulfadiazine which were required to exert bacteriostatic effect on Escherichia coli in a synthetic medium, were determined. Concentrations of para-aminobenzoic acid which caused a significant anti-sulfonamide activity were determined. Concentrations of urea which had no effect on bacterial growth were also determined.Combinations of these concentrations of sulfonamides and urea, proved to possess bacteriostatic action even in the presence of the sulfonamide inhibitor. |
Databáze: | OpenAIRE |
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